Lymphocyte transformation test for medicinal herbs yields false-positive results for first-visit patients.
نویسندگان
چکیده
We performed lymphocyte transformation tests (LTTs) for toki (angelicae radix) and ogon (scutellariae radix) on first-visit patients who had never taken Kampo medicines. LTTs for both herbs were positive in 12 of 14 patients, suggesting that LTTs for these herbs are unreliable for the diagnosis of Kampo medicine-induced liver injury.
منابع مشابه
Herbal medicine and false-positive results on lymphocyte transformation test.
In vitro mitogenic activity of 16 herbs and 3 Kampo (herbal medicine) formulae have been reported in experimental studies. It is not known how many herbs and Kampo formulae in total have mitogenic activity. Lymphocyte transformation test (LTT) is generally utilized to diagnose drug-induced liver injury. In LTT, mitogenic activity is assessed by measuring 3H-thymidine incorporation. The objectiv...
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عنوان ژورنال:
- Clinical and diagnostic laboratory immunology
دوره 10 3 شماره
صفحات -
تاریخ انتشار 2003